1. Modi, S., Gibson, T., Vigneswaran, G., Patel, S., Wheater, M., Karydis, I., Gupta, S., Takhar, A., Pearce, N., Ottensmeier, C. and Stedman, B., 2022. Chemosaturation with percutaneous hepatic perfusion of melphalan for metastatic uveal melanoma. Melanoma Research, Publish Ahead of Print/li>
2. Data on File, July 2022, REF-1063(v1.0).
3. Melanomafocus.org. 2023. UK Uveal Melanoma Guidelines. [online] Available at: https://melanomafocus.org/wpcontent/uploads/2022/06/2_UM_Guideline_v7_6.pdf [Accessed 16 March 2023].
4. Leitlinienprogramm Onkologie - S3 Guidelines Melanoma Germany. https://www.leitlinienprogrammonkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Melanom/Melanom_Version_3/LL_Melanom_Langversion_3.3.pdf [Accessed 16 March 2023]
5. Meijer, T., Burgmans, M., de Leede, E., de Geus-Oei, L., Boekestijn, B., Handgraaf, H., Hilling, D., Lutjeboer, J., Vuijk, J., Martini, C., van Erkel, A., van der Meer, R., Tijl, F., Speetjens, F., Kapiteijn, E. and Vahrmeijer, A., 2020. Percutaneous Hepatic Perfusion with Melphalan in Patients with Unresectable Ocular Melanoma Metastases Confined to the Liver: A Prospective Phase II Study. Annals of Surgical Oncology, 28(2), pp.1130-1141
6. Karydis, I., Gangi, A., Wheater, M., Choi, J., W1-3ilson, I., Thomas, K., Pearce, N., Takhar, A., Gupta, S., Hardman, D., Sileno, S., Stedman, B., Zager, J. and Ottensmeier, C., 2017. Percutaneous hepatic perfusion with melphalan in uveal melanoma: A safe and effective treatment modality in an orphan disease. Journal of Surgical Oncology, 117(6), pp.1170-1178.
7. Brüning, R., Tiede, M., Schneider, M., Wohlmuth, P., Weilert, H., Oldhafer, K. and Stang, A., 2020. Unresectable Hepatic Metastasis of Uveal Melanoma: Hepatic Chemosaturation with High-Dose Melphalan—Long-Term Overall Survival Negatively Correlates with Tumor Burden. Radiology Research and Practice, 2020, pp.1-7.
8. de Leede, E., Burgmans, M., Martini, C., Tijl, F., van Erkel, A., Vuyk, J., Kapiteijn, E., Verhoef, C., van de Velde, C. and Vahrmeijer, A., 2016. Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver. Journal of Visualized Experiments, (113).

1. Vogel, A., Gupta, S., Zeile, M., v on Haken, R., Brüning, R., Lotz, G., Vahrmeijer, A., Vogl, T. and Wacker , F., 2016. Chemosaturation Percutaneous Hepatic Perfusion: A Systematic Review. Advances in Therapy, 33(12), pp.2122-2138.
2. Artzner, C., Mossakowski, O., H efferman, G., Grosse, U., Hoffmann, R., Forschner, A., Eigentler, T., Syha, R. and Grözinger 4, G., 2019. Chemosaturation with percutaneous hepatic perfusion of melphalan for liver-dominant metastatic uveal melanoma: a single center experience. Cancer Imaging, 19(1).
3. Chemosat.com. IFU 2022. [online] Available at: [Accessed 1 March 2022]

1. Karydis, I., Gangi, A., Wheater, M., Choi, J., W1-3ilson, I., Thomas, K., Pearce, N., Takhar, A., Gupta, S., Hardman, D., Sileno, S., Stedman, B., Zager, J. and Ottensmeier, C., 2017. Percutaneous hepatic perfusion with melphalan in uveal melanoma: A safe and effective treatment modality in an orphan disease. Journal of Surgical Oncology, 117(6), pp.1170-1178.
2. Brüning, R., Tiede, M., Schneider, M., Wohlmuth, P., Weilert, H., Oldhafer, K. and Stang, A., 2020. Unresectable Hepatic Metastasis of Uveal Melanoma: Hepatic Chemosaturation with High-Dose Melphalan—Long-Term Overall Survival Negatively Correlates with Tumor Burden. Radiology Research and Practice, 2020, pp.1-7.
3. Vogel, A., Gupta, S., Zeile, M., v on Haken, R., Brüning, R., Lotz, G., Vahrmeijer, A., Vogl, T. and Wacker , F., 2016. Chemosaturation Percutaneous Hepatic Perfusion: A Systematic Review. Advances in Therapy, 33(12), pp.2122-2138.
4. Data on File, July 2022, REF-1063(v1.0).
5. Meijer, T., Burgmans, M., de Leede, E., de Geus-Oei, L., Boekestijn, B., Handgraaf, H., Hilling, D., Lutjeboer, J., Vuijk, J., Martini, C., van Erkel, A., van der Meer, R., Tijl, F., Speetjens, F., Kapiteijn, E. and Vahrmeijer, A., 2020. Percutaneous Hepatic Perfusion with Melphalan in Patients with Unresectable Ocular Melanoma Metastases Confined to the Liver: A Prospective Phase II Study. Annals of Surgical Oncology, 28(2), pp.1130-1141
6. Modi, S., Gibson, T., Vigneswaran, G., Patel, S., Wheater, M., Karydis, I., Gupta, S., Takhar, A., Pearce, N., Ottensmeier, C. and Stedman, B., 2022. Chemosaturation with percutaneous hepatic perfusion of melphalan for metastatic uveal melanoma. Melanoma Research, Publish Ahead of Print
7. Artzner, C., Mossakowski, O., H efferman, G., Grosse, U., Hoffmann, R., Forschner, A., Eigentler, T., Syha, R. and Grözinger 4, G., 2019. Chemosaturation with percutaneous hepatic perfusion of melphalan for liver-dominant metastatic uveal melanoma: a single center experience. Cancer Imaging, 19(1).

1. Melanomafocus.org. 2023. UK Uveal Melanoma Guidelines. [online] Available at: https://melanomafocus.org/wpcontent/uploads/2022/06/2_UM_Guideline_v7_6.pdf [Accessed 16 March 2023].
2. Leitlinienprogramm Onkologie - S3 Guidelines Melanoma Germany. https://www.leitlinienprogrammonkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Melanom/Melanom_Version_3/LL_Melanom_Langversion_3.3.pdf [Accessed 16 March 2023]
3. Karydis, I., Gangi, A., Wheater, M., Choi, J., W1-3ilson, I., Thomas, K., Pearce, N., Takhar, A., Gupta, S., Hardman, D., Sileno, S., Stedman, B., Zager, J. and Ottensmeier, C., 2017. Percutaneous hepatic perfusion with melphalan in uveal melanoma: A safe and effective treatment modality in an orphan disease. Journal of Surgical Oncology, 117(6), pp.1170-1178.
4. Brüning, R., Tiede, M., Schneider, M., Wohlmuth, P., Weilert, H., Oldhafer, K. and Stang, A., 2020. Unresectable Hepatic Metastasis of Uveal Melanoma: Hepatic Chemosaturation with High-Dose Melphalan—Long-Term Overall Survival Negatively Correlates with Tumor Burden. Radiology Research and Practice, 2020, pp.1-7.
5. Vogel, A., Gupta, S., Zeile, M., v on Haken, R., Brüning, R., Lotz, G., Vahrmeijer, A., Vogl, T. and Wacker , F., 2016. Chemosaturation Percutaneous Hepatic Perfusion: A Systematic Review. Advances in Therapy, 33(12), pp.2122-2138.
6. Artzner, C., Mossakowski, O., H efferman, G., Grosse, U., Hoffmann, R., Forschner, A., Eigentler, T., Syha, R. and Grözinger 4, G., 2019. Chemosaturation with percutaneous hepatic perfusion of melphalan for liver-dominant metastatic uveal melanoma: a single center experience. Cancer Imaging, 19(1).
7. https://clinicaltrials.gov/ct2/show/NCT02678572?term=FOCUS&cond=Uveal+Melanoma&draw=2&rank=3

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